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Gurung, R

This ensures rapid absorption and immediate availability at the cellular level

doi: 10.3389/fphar.2024.1402138 96 LaferrreBHartABBowersCY

Hartmann et al., 2000)

HeLa cells assay AtSNX1 and MmSNX1 CDS were cloned into the plasmid pLV-IRES-EGFP to generate GFP-tagged forms and then infected HeLa cells with lentiviruses packaged using the pLV-IRES-AtSNX1-EGFP and pLV-IRES-MmSNX1-EGFP plasmids, respectively, to obtain HeLa-AtSNX1-GFP and HeLa-MmSNX1-GFP cell lines

This leads to the cleavage and translocation of AIF from the mitochondrial intermembrane space to the nucleus, phosphorylation of the histone H2A family member H2AX, mitochondrial release of the death-inducing protein Smac/direct IAP-binding protein with low PI (DIABLO), and inhibition of the anti-apoptotic protein X-linked inhibitor of apoptosis (XIAP)