Food and beverage category impact by GLP-1 users Beyond food groups, the impact of GLP-1 is also influencing consumer packaged goods (CPGs) and ingredient companies
Cleavable linkers in antibody-drug conjugates
Serious adverse events and complications of these medications may include Gastroparesis (paralysis of the stomach), NAION vision loss, Ileus, Pancreatitis, Wernickes Encephalopathy, Bowel obstruction (blocked intestine), Malnutrition requiring hospitalization, and Pulmonary aspiration while under anesthesia or during surgery
In SURMOUNT-1, adults with obesity or overweight without diabetes were randomized to tirzepatide or placebo for 72 weeks
These findings align with the effects of semaglutide observed in the study, which, beyond reducing astroglial activation and normalizing AQP4 and Cx43 distribution, contributed to decreased caspase-3 activation and reduced neuronal damage in the ventromedial nucleus of the hypothalamus
Their discovery of an allosteric binding site, known as the switch II pocket (SWIIP