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The GHK tag promoted crystallization, with various residues (His, Asp, His/Pro) from symmetry molecules completing the copper(II) square-pyramidal coordination sphere

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Following the intervention, 14 (23.3%) had a normal condition, 13 (21.7%) mild, 19 (31.7%) moderate, and 11 (18.3%) had severe depression scale at the 3 rd week of treatment

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Acknowledging this complexity underscores the need for caution when generalizing our findings and emphasizes the importance of standardized approaches in future research

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