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(December 2001)

319 In addition, adiponectin is an anti-inflammatory adipokine that mediates fatty acid -oxidation (FAO), glucose use, and suppression of fatty acid synthesis

There is no benefit to reaching the maximum dose quickly

Major obesity-related disorders include: Type 2 diabetes mellitus Hypertension Cardiovascular disease Non-alcoholic fatty liver disease Obstructive sleep apnea Osteoarthritis Chronic spine disorders For physicians working in pain medicine , obesity plays a crucial role in the development and progression of degenerative musculoskeletal diseases