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2.7 m, 3.0 50 mm) using positive-mode electrospray ionization with 1% acetonitrile in H 2 O (containing 0.1% formic acid) for the first 2 min, then a linear gradient of 195% for 9 min and finally 95% acetonitrile for 3 min with a flow rate of 0.6 ml min 1

During the initial treatment of patients with pernicious anemia, serum potassium must be observed closely the first 48 hours and potassium replaced if necessary

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Bausch J

A., & Greenberg, M

Pre-existing inborn errors of sulfur-amino-acid metabolism (e.g., homocystinuria) represent an absolute contraindication because parenteral methionine can exacerbate elevated homocysteine concentrations and associated thrombotic risk