Researchers are exploring its potential in metabolic health, longevity, and other cellular processes in 2026
Nevertheless, use of metformin may decrease vitamin B 12 status: a meta-analysis of four short-term intervention trials (up to 4 months duration) in patients with type 2 diabetes found that metformin use decreased serum cobalamin concentrations by 57 pmol/L, which could have clinical implications if such patients have suboptimal vitamin B 12 status (146)
Emotional Toll: The repetitive cycle of trying and failing to lose weight through these methods often leaves individuals feeling defeated
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Pernicious anaemia (NG239) NICE