Verdict: High credibility given research provenance
However, without appropriate nutritional guidance and support from healthcare professionals, there is a real risk that reduced food intake could compromise dietary quality, meaning people may not get enough protein, fibre, vitamins, and minerals essential for maintaining overall health. Guidelines from the National Institute for Health and Care Excellence (NICE) recommend semaglutide as an option for weight management for individuals who meet specific criteria, such as a body mass index (BMI) of at least 35.0 kg/m2 and comorbidity (that is, they also have other conditions such as type 2 diabetes, cardiovascular disease, etc)
[Google Scholar] D-Glutamate is metabolized in the heart mitochondria
So these were the kinds of explanations people put up
Another theory is that semaglutide may alter the reward system in the brain that is involved in food cravings and addiction
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