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There is an optimal dosing range below which effects are minimal and above which effects actually diminish

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doi: 10.1210/edrv-14-2-133 48 LiYChenLGaoYZouXWeiF

Without adequate ALA, the mitochondrial assembly line stalls, contributing to the profound cellular fatigue seen in ME/CFS and Long COVID

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The pathogenesis of CIPN is multifactorial, involving oxidative stress, neuroinflammation, neurotrophic factor depletion, and mitochondrial dysfunction ( Plant-derived foods have emerged as promising candidates for CIPN prevention due to their unique multi-target antioxidant properties