Effects of mitochondrial-derived peptides (MDPs) on mitochondrial and cellular health in AMD
At concentrations lower than those of DON, JHU395 has been found to decrease the growth and increase the apoptosis of high-MYC medulloblastoma cell lines, thereby prolonging the survival of treated animals (100)
doi: 10.1016/j.phrs.2007.05.001, 64
This might be due to Wallerian and neuronal degeneration that is initiated as soon as axons are intersected during the acute phase of disease [34, 35]
Future research should explore D-amino acid metabolism, chiral-specific effects, and the development of derivatives and complexes
Dheyab M, Abdul Aziz A, Moradi Khaniabadi P, Jameel M, Oladzadabbasabadi N, Mehrdel B (2022) Monodisperse gold nanoparticles a review on synthesis and their application in modern medicine