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Patients should be aware that key safety considerations include: Hypersensitivity to the active substance or excipients Pregnancy or breastfeeding Risk of pancreatitis and gallbladder disease Potential for dehydration with severe gastrointestinal side effects A thorough medical assessment, including review of current medications and comorbidities, is essential before initiating treatment

After one year, 48% had lost less than 5% of their body weight, while 4% had lost more than 15% of their body weight

It also requires access to a reliable supply of these drugs, which is far from a given amid widespread shortages

Options include semaglutide and tirzepatide

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There are also side effects