The Journal of clinical investigation, 1993, 92(5): 2368-2376
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developed a model of Ox-LDL-induced ferroptosis in HUVECs, showing that CTRP13 intervention increased antioxidant enzyme expression, preventing AS and protecting endothelial cells from ferroptosis ( / mice by reducing mitochondrial damage, boosting glutathione and superoxide dismutase levels, and decreasing LPO and MDA levels
While clinical trials conducted in Croatia in the early 2000s determined BPC 157 to be safe and effective in humans for the treatment of inflammatory bowel disease, there appears to be a lack of trials conducted in the U.S
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