This may be due to the drugs unpleasant side effects
Thus GLP-1 was shown to regulate a number of diverse functions: reduction in digestive enzyme secretion, slowing of gastric motility, increases in heart rate and blood flow, increased bone remodeling, and suppression of appetite (via hypothalamic and brainstem nuclei)
Clinicians should factor in the possible risks of long-term treatment at higher doses as well as drug costs and availability when deciding whether to prescribe GLP-1 receptor agonists among patients with obesity
Texas Tech University Health Science Center at Permian Basin, Midland, Texas (Yadav, Jain)
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