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Prickaerts J, Moechars D, Cryns K, Lenaerts I, van Craenendonck H, Goris I, et al

In August 2025, Novo Nordisk announced that the FDA has approved WEGOVY as the first GLP-1 receptor agonist for adults with Metabolic Dysfunction-associated Steatohepatitis (MASH) who have moderate to advanced fibrosis, excluding cirrhosis, in combination with diet and exercise

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Additional subgroup- and sensitivity analyses yielded results similar to the main analysis

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Methionine is an amino acid that can either be used to build a protein, or it can give up its methyl group so that methylation can occur