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There is evidence from a previous meta-analysis that GLP-1RA confer a similar reduction in MACE in both sexes, whereas SGLT-2 inhibitors reduce the risk of MACE more in men than in women [31]
We don't know the long term ramifications
Everyone's biology is different, so your timeline may vary
DPP-4 inhibitors: DPP-4 inhibitors work by inhibiting the activity of dipeptidyl peptidase-4 (DPP-4), which reduces the breakdown and inactivation of the incretin GLP-1 (glucagon-like peptide-1), leading to increased endogenous levels of GLP-1
Left panel (Mechanism of Action & Pharmacodynamics) : Imipramine inhibits the serotonin transporter (SERT) and norepinephrine transporter (NET), resulting in increased synaptic concentrations of serotonin and norepinephrine (dual monoamine reuptake inhibition)
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