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Unfortunately, studies on this topic have mainly focused on normalising serum B12 concentrations with oral supplementation and should be interpreted with caution since the specific goal of treatment in symptomatic B12 deficiency is alleviating symptoms, and NOT to normalize B12 concentrations in the blood

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Some protocols might also use intramuscular injections (into muscle), though subcutaneous is more common due to better tolerability

But once water is added, freezing becomes destructive

Conversely, adding 1.2 mL instead of 1.0 mL dilutes to 8.33 mg/mL, and every dose is about 17% weaker than planned