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Biochem Pharmacol 34:22052207 Roman HB, Hirschberger LL, Krijt J, Valli A, Koich V, Stipanuk MH (2013) The cysteine dioxgenase knockout mouse: altered cysteine metabolism in nonhepatic tissues leads to excess H 2 S/HS- production and evidence of pancreatic and lung toxicity

Importantly, 32.5% of patients enrolled did not have T2DM and 14.5% had an eGFR below 30 mL/min/1.73 m 2 , demonstrating the benefit of dapagliflozin across a range of kidney function regardless of diabetes status [47]

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Cardiovascular Outcomes, Safety, and Tolerability With Oral Semaglutide

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