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For laboratory research protocols, dose-finding studies in cell or animal models should always be designed based on the specific research question and validated reference literature

Cytosolic and mitochondrial glutathione peroxidases (cGPXs or GPX1) reduce only soluble hydroperoxides, such as H 2 O 2 , and some organic hydroperoxides, such as hydroperoxy fatty acids, cumene hydroperoxide or t-butyl hydroperoxide

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Variations in genes such as IL-6, which encodes interleukin-6, a cytokine involved in inflammation and immune response, can influence the extent and duration of inflammation following an injury

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