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This is a 1.7 m2 low-flow polyphenylene surface area filter (Kuf = 13 ml/h/mmHg) where small molecule removal and correction of metabolic acidosis takes place by diffusive mechanism.47 It is at this level that the net water balance of the technique is also produced by ultrafiltration to achieve the patient's target dry weight.29,47,50 Differential characteristics of HFR with respect to OL-HDF Although both techniques combine diffusion and convection in order to improve the purification of medium and large molecules, there are notable differences between the two techniques beyond the adsorptive capacity associated with HFR (Table 2)

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