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It is well established that activation of GLP-1R in pancreatic beta cells results in glucose-dependent potentiation of insulin secretion and a subsequent decrease of the blood-glucose level 2

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(PubMed) Husebye ESN, Wendel AWK, Gilhus NE, Riedel B, Bjork MH

Furthermore, PDA is a potent stimulator of F-actin production in fibroblasts

Playdon MC, Bracken MB, Sanft TB, Ligibel JA, Harrigan M, Irwin ML

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