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In parallel, Eli Lilly developed tirzepatide (Mounjaro)--a dual GLP-1 and GIP receptor agonist

Patients experiencing symptoms such as nausea, vomiting, or abdominal pain may need to undergo this study to determine if delayed gastric emptying is the cause

Reduced potency means reduced effectiveness, which can mean a longer protocol to achieve the same results, additional medical consultations, and the psychological cost of plateau frustration

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The body requires a mechanical signal to justify the energy cost of maintaining muscle tissue