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SIRT1 is a histone deacetylase, which may regulate the transcriptional activity of BMAL1/CLOCK, forming a metabolic feedback loop again between the circadian clock system and metabolism (Nakahata et al., 2009

A randomized, open labeled study comparing the serum levels of cobalamin after three doses of 500 mcg vs

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The elevated expression of synaptic and axonal proteins suggests that extensive connectivity is essential for cross-modal integration, which may be vulnerable to synaptic loss