Slow-Titration Protocol: Conservative Escalation for Nausea-Prone Users The Phase 2 trial protocol explicitly allowed prescribers to delay or skip dose escalation at physician discretion for participants who did not tolerate the protocol-specified increase (Jastreboff et al., NEJM 2023, Supplementary Appendix)
A large analysis of 37 trials involving 2,292 participants concluded that L-carnitine significantly reduced body weight, BMI, and fat mass
The combination of the IRAs restructured benefit with the coming wave of small-molecule specialty drug patent expirations (CDK4/6 inhibitors, oral oncology agents) will likely accelerate generic uptake rates for these drugs compared to historical patterns
Similarly, no correlations were found with inflammatory markers, suggesting that the observed decline in ADC is not mediated by an increase in inflammation
New York, NY: Pfizer Inc
The story of glutathione, the basic intracellular thiol-containing compound, ranges throughout different scientific fields