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If UTI risk from dehydration concerns you with one, switching to the other is unlikely to make a meaningful difference

Behavioral, neuropharmacological, electrophysiological and neuroanatomical results obtained here support a direct impact of central GLP-1 activation to increase central serotonin neurotransmission, a relationship discovered to be critical for GLP-1-induced weight-loss or weight-loss maintenance and hypophagia

And what he found was that they really run the gamut

While semaglutide offers significant benefits for weight loss and blood sugar control, it can have several side effects, including diarrhea, vomiting, constipation, kidney damage, and fatigue

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Ann Surg 276(5):799-805, 2022