semaglutide heart benefits vs Tirzepatide 💉⚖️ Both are powerful medications for diabetes and weight loss, but tirzepatide's dual GIP + GLP-1 action may lead to even greater weight loss and glucose control. Semaglutide offers Semaglutide and the Heart: Focus

Tirzepatide is a dual GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptor agonist

Triantafyllou, K., Chang, C., Pimentel, M

The emergence of NAWE in this patient underscores the importance of considering thiamine deficiency as a potential consequence of GLP-1 agonist-induced appetite suppression and altered nutrient intake or absorption

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Among 169,649 patients with MASLD, GLP-1 receptor agonist initiation was linked to significantly lower probability of incident cirrhosis [adjusted hazard ratio (aHR): 0.86, 95%CI: 0.80-0.93], hepatic decompensation (aHR: 0.77, 95%CI: 0.65-0.90), and hepatocellular carcinoma (HCC) (aHR: 0.79, 95%CI: 0.68-0.92) over a median follow-up of 3.5 years compared to non-users

doi: 10.6065/apem.2017.22.3.145 106 WoltersTLCNeteaMGRiksenNPHermusARMMNetea-MaierRT