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Preclinical models commonly use doses ranging from 100mcg to 500mcg per administration, with frequency varying from daily to twice-weekly depending on the biological pathway under investigation

Indeed, iron is required for synthesis of iron-sulfur clusters (ISCs), which are integral components of the electron transport chain (ETC), and heme, a porphyrin ring complexed to iron that serves as a prosthetic group in hemoproteins involved in electron transport and enzymatic catalysis

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regular blood monitoring is required to avoid this complication