Another study, released in August of 2025, found that people taking semaglutide drugs like Ozempic or a tirzepatide drug were 1.76 times as likely to develop NAION (non-arteritic anterior ischemic optic neuropathy) than those taking other types of type 2 diabetes drugs
Castoldi G, Carletti R, Ippolito S et al (2020) Renal anti-fibrotic effect of sodium glucose cotransporter 2 inhibition in angiotensin II-dependent hypertension
However, these patients had multiple risk factors for b12 deficiency beyond semaglutide use, including previous gastric surgery that permanently alters stomach anatomy and reduces intrinsic factor production
August 2022
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What if I experience side effects at higher doses