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For example, switching where the shot is given can help avoid irritation

Once the pellets are inserted, it is not easy to modify the dosage or discontinue treatment until they have dissolved

This makes it particularly relevant in clinical contexts where someone has gut lining compromise alongside systemic inflammation, for example, long-term NSAID use for chronic pain

Patients who are pregnant, breastfeeding, managing cancer-related concerns, taking certain medications, or dealing with complex medical conditions should speak with a qualified provider first.

Injury type significantly influences timeline

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