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Apolipoprotein E \({\varvec{\varepsilon \) 4 is also known to exacerbate tau neurofibrillary tangle-related neurodegeneration, microglial responses and neuroinflammation, astroglial activity, and blood brain barrier disruption [82]

Medications affecting clotting, such as anticoagulants (including warfarin and direct oral anticoagulants), may also contribute to increased menstrual blood loss

Studies have shown that chronic hyperglycemia and recurrent hypoglycemia in patients with diabetes reduce brain network efficiency [108], impair hippocampal neurogenesis and memory [109], and lead to microstructural changes in white matter and reduced gray matter density [110]

Enhanced energy and confidence: As weight is managed effectively, clients often report improved energy levels, mobility, and quality of life

As with Botox, defer to the practitioner who performed the injectable

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