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Early identification of hepatic steatosis, fibrosis risk, and related metabolic complications enables timely intervention, whether through lifestyle modification, optimization of glycemic control, or initiation of agents such as GLP-1 RAs, dual or triple incretin agonists, which have demonstrated favorable effects on steatosis, inflammation, and weight regulation across phase 2 and phase 3 trials included in this review

Statistical analysis All statistical analysis was completed using either R or GraphPad Prism 9/10

Stress and Cravings Hormonal changes affect mood and stress response

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Following an oral dose, NAC absorbs rapidly, reaching its peak plasma concentration within 1 to 2 hours, and has a relatively short terminal half-life of approximately 5.5 to 6.25 hours

Hemolysis has been clearly associated with emitting proinflammatory signals through releasing DAMPs [224]