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Oral formulations were also developed.1,3,5 GLP-1 receptor monoagonists for the treatment of obesity: liraglutide and semaglutide The first molecule to be marketed for the treatment of obesity was liraglutide (LIRA), administered via daily subcutaneous injection, which became available in 2014

The author holds equity interest in RNA Therapeutics Inc, DEI Biopharma Inc, Abyolo, and BioRx Inc, but none of these create any conflict of interest for this paper

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