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The Journal of Clinical Investigation, 92 (5), 2368-2376.

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Here's a quick comparison of methylcobalamin (the natural form) and cyanocobalamin (the synthetic option): Methylcobalamin Naturally occurring form, found in animal-based foods such as meat, fish, eggs, and dairy Considered the "active" form and is readily usable by the body Cyanocobalamin Synthetically produced and not naturally occurring More stable and cost-effective to produce Converted by the body into active forms like methylcobalamin or adenosylcobalamin Absorption And Bioavailability Methylcobalamin and cyanocobalamin differ in their absorption and retention in the body

It requires conversion before your body can use it, and often, this step is skipped by the body, which means that you pass it through your system without absorbing it

But, patients need training from a healthcare provider on how to do it right