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This network upregulates the expression of serine hydroxymethyltransferase-2 ( SHMT2 ) for dTTP synthesis and amino acid transporters, such as solute carrier family 1 member 1 ( SLC1A1 ) and solute carrier family 7 member 8 ( SLC7A8) , for GSH biosynthesis

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There were two methods used for internal reference in the included studies, both phosphocreatine/creatine and water-scaling

In summary, A549 cells (ATCC, CCL-185) were cultured and maintained at 37 C and 5% CO 2 in high-glucose (0.45% w/v) Dulbeccos Modified Eagle Medium (DMEM) with 10% (v/v) heat-inactivated fetal bovine serum, penicillin (50 U/mL), and streptomycin (50 g/mL)

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Importantly, the compound has shown a good safety record, with very few side effects reported