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For people who already have a tendency toward constipation, semaglutide can make the problem worse

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Chronic hyperglycemia in diabetes downregulates GIP receptor (GIPR) expression and impairs GIP-mediated insulin secretion [21], rendering high-doses of GIP infusions ineffective [22]

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It is not known if Wegovy passes into your breast milk

This contradictory impact underscores the nuanced nature of GLP-1 drugs on reproductive health