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doi:10.3389/fendo.2022.1004044 4

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Headache : Some patients may report mild headaches, which typically resolve on their own or with the use of over-the-counter analgesics

Retinol's forced turnover on already-compromised skin often causes more problems than it solves, especially at over-the-counter concentrations where efficacy is lower but irritation persists

In Greer, J.P., Foerster, J., Rodgers, G.M., Paraskevas, F., Glader, B., Arber, D.A., Means Jr., R.T