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In recent years, small-format antibody fragments [such as Fab fragments, single chain variable fragments (scFv), and designed ankyrin repeat proteins (DARPins)] have demonstrated unique advantages in novel ADC designs [22,130,131]

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A review of treating adults with depressive symptoms found that acetyl-L-carnitine significantly reduced depressive symptoms versus placebos, and showed similar effectiveness compared to established antidepressants (7)

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