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Mild injection site irritation is common

"Semaglutide, the active ingredient in Ozempic, mimics GLP-1, a hormone that helps regulate blood sugar levels and makes you feel fuller for longer," explains Caroline Apovian, MD, Co-Director of the Center for Weight Management and Wellness at Brigham and Women's Hospital

Because the first dose is typically a low loading dose (0.25 mg), the body is being gently introduced to the medication to minimize stress on the digestive system

Diabetes Care (2009) 32(7):122430

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