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These findings suggest that a decrease in anti-oxidative agents is a risk factor for glaucoma onset and progression

Izquierdo-Alventosa et al

Methylcobalamin degrades more rapidly

Mechanistically, overexpression of CD36 increases lipid peroxidation, mitochondrial ROS production, the labile iron pool, and especially Fe 2+ content

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These radicals react about 1,000 times faster with -tocopherol (vitamin E) than with unsaturated lipids