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In fact, one of the patients in the phase 2 study for BED died because of toxicology findings consistent with a methamphetamine overdose. So clearly this concern deserves close scrutiny

FDA-approved drugs undergo a long and rigorous process of clinical trials to prove their safety, effectiveness, and quality before they can be marketed to the public. Compounded drugs, even from 503B facilities, do not go through this same pre-market approval process

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Back Lund, PK (2005) 'The discovery of glucagon-like peptide 1', Regulatory Peptides , 93-96

Especially, their analgesic effects are achieved without the development of tolerance, offering a significant advantage over traditional pain management strategies