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Mol Reprod Dev 42:415424

The one percent of calcium not stored in the skeletal system performs vital functions including transmission of nerve impulses, muscle contraction, activation of several coagulation factors involved in blood clotting, modulation of wound healing, communication between immune cells, insulin secretion from pancreatic beta-cells, and cellular signaling

In October 2022, the regulator issued a CRL, requesting additional information and analysis related to the infusion device and drug product across several areas of the New Drug Application (NDA)

Free radicals are unstable molecules that the body produces as a response to environmental and other pressures that lead to signs of aging