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Using Ozempic for weight loss is considered an unofficial, off-label indication so your doctor will write your prescription as private

The key consideration with semaglutide specifically is the gastrointestinal side effect profile

The guide on when weight loss begins on semaglutide gives context on where you are likely to be in the metabolic adjustment curve relative to a test, which helps you understand what side effects you might reasonably expect

44 In the latest clinical trials, namely the STEP-HFpEF and STEP-HFpEF-DM trials, semaglutide resulted in a significant reduction in C-reactive protein levels versus placebo in a pooled analysis of the two trials (43% versus 10%, respectively)

This can be due to dehydration, the effects of medication, or strain on the kidneys

If you have any questions or concerns about a medication, please talk to your doctor or pharmacist.