When used in therapeutic doses, no side effects are observed, but from the nervous system and senses may be depression or agitation, disorientation, vomiting, sweating, visual disturbances, tremor, convulsions, respiratory depression, apnea
The body interprets sustained amylin signaling as a signal to stop eating, and sometimes that signal overshoots into actual nausea
For example, certain types of peptide linkers are designed to be cleaved by enzymes abundant in tumor cells to selectively release drugs to these cells
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