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[177], including twenty-two RCTs involving 1377 patients, a poor performance was observed for metformin when compared to other antidiabetic drugs such as the GLP-1 receptor agonist for hepatic fat content, the MASLD activity score, ALT, AST, GGT, and body weight

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Your body responds to this "challenge" by upregulating its production of glutathione

But if you dont change your eating habits, youre more likely to suffer from side effects like nausea, constipation, diarrhea, or vomiting because of this reason

J Clin Endoc Metab

10.2174/13816128130111 77 SikiricP.SeiwerthS.RucmanR.TurkovicB.RokotovD