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Due to the imbalance of excitatory/inhibitory (E/I) mechanisms in epilepsy acting as the major trigger for seizure activity, the involvement of the excitatory neurotransmitter glutamate and the inhibitory neurotransmitter GABA is fundamental [80]

Supernatants were collected and centrifuged at 1000 g , 4 C for 10 min to remove dead cell debris

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10.1111/j.1600-0625.2012.01483.x 126 KimN.-H.ChoiS.-H.LeeT

Code availability R code used for data analysis is available via the Open Science Framework at References Jelen L

They operate at the level of individual receptors, growth factors, and gene expression pathways