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FDA's 2024 review states the mechanism of action is still unknown, which limits how confidently any specific physiological effect can be predicted in humans

3c) G6PD-d may therefore promote proatherogenic ferroptosis in a variety of cell types including VECs, VSMCs, macrophages, and other immune cells even in the absence of RBC destruction

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So, we really dont know

TB-500 is a structurally specific G-actin sequestering peptide with the strongest evidence in cardiac progenitor biology, dermal and corneal wound healing, and migratory contributions to soft-tissue repair

J Metab Bariatr Surg 2022