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This contributes to the broader evidence base for the medicine's safety profile and is an important part of how medicines are evaluated before licensing

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The STEP 4 withdrawal trial showed that most participants regained approximately two-thirds of lost weight within one year of discontinuation, confirming that semaglutide treats obesity chronically rather than curing it

Examples of nutrients of concern include iron, calcium, magnesium, zinc, and vitamins A, D, E, K, B1, B12, and C

For medically supervised weight loss, accessing Medifast products directly through a physician or registered dietitian avoids the coach-recruitment dynamic and adds credentialed clinical oversight

Morgan JE