Good candidates generally have stable health status, understand the experimental nature of the therapy, and commit to appropriate monitoring protocols
To our knowledge, rare human studies have evaluated the association between serum vitamin B12 and NAFLD
Patients with gut conditions, including coeliac, Crohn's and significant IBS, are the third group
Dietary sources of CoQ10 come mainly from beef heart, pork, chicken livers and fish
nausea occurs in up to 31% of tirzepatide initiators Who should not switch / Patients with personal or family history of medullary thyroid carcinoma or MEN2 syndrome (contraindication shared by both drugs) Why Patients Switch from Semaglutide to Tirzepatide Switching GLP-1 therapies is not a fringe scenario
A 2025 University of Virginia study concluded that while GLP-1 drugs significantly reduce body weight and adiposity, they do so "with no clear evidence of cardiorespiratory fitness enhancement"a critical finding given that cardiorespiratory fitness is among the most potent predictors of all-cause and cardiovascular mortality [48]
