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However: Patients with BMI over 45 Severe sleep apnea Advanced type 2 diabetes Longstanding obesity may achieve more durable remission through bariatric surgery

Key findings Tirzepatide treatment led to broad improvements in cardiometabolic risk factors compared with placebo across both trials

The researchers found that in trial 1, the mean change in AHI was 25.3 and 5.3 events per hour with tirzepatide and placebo, respectively, at week 52 (estimated treatment difference, 20.0 events per hour)

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Target doses of 9 mg and 12 mg

More water means a more dilute solution and easier measurement of small doses, but the total amount of tirzepatide in the vial remains the same