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While IBS itself is not a contraindication for these FDA-approved medications, the decision requires careful consideration of your specific IBS subtype, symptom severity, and potential for gastrointestinal side effects

This design ensures spatial separation of the GLP-1 N-terminus from the albumin moiety, preserving receptor-binding capacity and maintaining full biological activity

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Conversely, MT2 interacts with several receptors (MC1R, MC3R, and MC4R), with further impact on metabolic and sexual functions

People with severe stomach or digestion problems (like gastroparesis)

Alternatives like GLP-1 medications are often favored because they work through the body's natural regulatory systems, offering benefits beyond weight loss, such as cardiovascular improvements