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Recombinant variant of ciliary neurotrophic factor for weight loss in obese adults a randomized, dose-ranging study

This estimate decreased to a null value after confounding factors were accounted for (hazard ratio 1.02, 95% CI 0.85 to 1.23)

Most studies have looked at berberine for 3-6 month periods (sometimes up to a year), but not much longer than that

Adding a pinch of high-quality salt to water or using electrolyte packets addresses this quickly