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GLP-1 has a very short half-life of only 1 to 2 minutes, whereas oxyntomodulin has a circulating half-life of 12 minutes, and the predicted half-life of glicentin is around 30 to 35 minutes Clinical Studies Early-stage biomarker for nonalcoholic fatty liver disease (NAFLD) Circulating levels of GLP-1, GLP-2, glicentin, oxyntomodulin, glucagon, MPGF were measured in individuals with early stage NAFLD , biopsy proven NAFLD and nonalcoholic steatohepatitis [NASH] Patients in early stages of NAFLD demonstrated higher fasting MPGF and lower incremental increase of glicentin during oral glucose tolerance test than controls

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